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9780199685028: Economic Evaluation in Clinical Trials (Handbooks in Health Economic Evaluation)
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It is becoming increasingly important to examine the relationship between the outcomes of a clinical trial and the costs of the medical therapy under study. The results of such analysis can affect reimbursement decisions for new medical technologies, drugs, devices or diagnostics. It can aid companies seeking to make claims about the cost-effectiveness of their product, as well as allowing early consideration of the economic value of therapies which may be important to improving initial adoption decisions. It is also vital for addressing the requirements of regulatory bodies.

Economic Evaluation in Clinical Trials provides practical advice on how to conduct cost-effectiveness analyses in controlled trials of medical therapies. This new edition has been extensively rewritten and revised; topics discussed range from design issues such as the types of services that should be measured and price weights, to assessment of quality-adjusted life years. Illustrative materials, case histories and worked examples are included to encourage the reader to apply the methods discussed. These exercises are supported with datasets, programmes and solutions made available online.

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About the Author:

Henry A. Glick, Professor of Medicine, Division of General Internal Medicine, Perelman School of Medicine; Professor of Health Care Systems, Wharton School; Senior Fellow, Leonard Davis Institute of Health Economics; Associate Scholar, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, USA,Jalpa A. Doshi, Associate Professor of Medicine, Division of General Internal Medicine, Perelman School of Medicine; Director, Economic Evaluations Unit, Center for Evidence-Based Practice; Director, Value-Based Insurance Design Initiatives; Center for Health Incentives; Senior Fellow, Leonard Davis Institute of Health Economics; Associate Scholar, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, USA,Seema S. Sonnad, Director of Health Services Research, The Value Institute, Christiana Care Health System, USA

Henry A. Glick, Ph.D. received an M.A. and Ph.D. in Public Policy Analysis from the University of Pennsylvania. He has more then 25 years of experience conducting economic assessments of medical therapies. He specializes in economic evaluations conducted as part of clinical trials. Henry served on the Randomized Clinical Trial-Cost Effectiveness Analysis (RCT-CEA) Task Force and the Task Force on Good Research Practices on Transferability of Economic Data in Health Technology Assessment, both chartered by the International Society of Pharmaceutical Outcomes Research (ISPOR) to develop guidance documents related to these issues.
Review:

"Economic Evaluation in Clinical Trials, 2nd Edition" is an sophisticated handbook for building economic assessment into clinical research. A solid cost-benefit analysis is essential to justify the high price (and development cost) of many medicines and medical devices." --Journal of Clinical Research Best Practices


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  • PublisherOxford University Press
  • Publication date2014
  • ISBN 10 0199685029
  • ISBN 13 9780199685028
  • BindingPaperback
  • Edition number2
  • Number of pages272
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